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The 6 Best Vitamin/Supplement Subscription Boxes in 2025 – Readers’ Choice Awards

ByKathryn BrookeJan 2, 2025 |

Struggling to pick the right vitamins and supplements to support your unique health goals and needs? We completely understand! It's easy to feel overwhelmed nowadays with the countless number of health supplements that have flooded the market. Plus, new personalized vitamin companies seem to be emerging nearly every month (each claiming to offer exactly what your body needs) which makes it incredibly challenging to zone in on a single brand.

Thankfully, there are a handful of vitamin subscription services that have risen above the competition and offer the highest quality vitamins and supplements available today. These brands use optimal forms of nutrients in their products, abide by strict quality testing methods, and are transparent about their ingredient sourcing. And the best part? They've been tested by and voted on by our very own readers at MSA.

Every year, we ask our readers to share their top recommended subscriptions of all types. Then we ask our experts to share what they know about each subscription to make it easy for you to know which subscription is right for you. Below, you’ll find our readers’ top choices for the best vitamin subscriptions and supplement subscriptions in 2025.

Read on for our reader’s recommendations for the best vitamin subscription boxes and supplement subscription boxes currently available. If we missed anything, drop us a comment. If you’ve tried one of these services, be sure to leave a quick review (even if you had a poor experience — your review can help other readers avoid subscription remorse).

1. Hum Nutrition

The Best Vitamin Subscription For Women's Health Needs

The Cost: Supplements range from $10-$60 per bottle (30-day supply). Save with bundles.

What This Vitamin Subscription Delivers:

Looking to start a healthier lifestyle? Not sure where to begin? Let Hum Nutrition help.

Hum Nutrition stands out among other vitamin subscriptions due to the extent of their personalization. This vitamin subscription service offers curated supplement plans based on your personal dietary needs.

To get started, fill out a short personal quiz, and then a Hum Nutrition nutritionist will build a unique plan. You’ll still have the ability to edit your shipment — pick and choose the vitamins that focus on the areas most important to you, and you’re good to go. The pricing is affordable, and you’ll get discounts for larger orders.

Hum carries 38 vitamin supplements that address a range of health, beauty, and mood concerns. We love their tongue-in-cheek supplement names like "Gut Instinct," "Hair Sweet Hair," and "Here Comes The Sun." And their packaging includes a brief description of each product's purpose so you know exactly what you're reaching for.

Most of Hum's supplements are vegan and non-GMO, those that aren't are marked clearly on the labels.

Pros

Online quiz creates a personalized vitamin plan.

Able to add and remove vitamins and supplements.

There are dietary supplements for a wide range of specific health concerns

Cons

Some supplements are expensive ($40+ per bottle)

Not geared toward men (but men can still use most products)

Almost all products are blends, not single ingredients

What Readers Say:

“Their gummy supplements are delicious!” – Piper

Shipping: Orders of $50 or more ship free to the U.S. For orders under $50, a $5.95 shipping fee applies within the U.S. and $12.95 for international destinations.

Starting at $26.00

If you want to learn more, check out all our HUM Nutrition reviews.

2. Care/of

Best Vitamin Subscription for Unique Supplement Forms

The Cost: Products range from $7-$32 per bottle/pack (30-day supply).

What This Vitamin Subscription Delivers:

Do you struggle to maintain a healthy supplement routine? Let Care/of take all the pain out of buying (and taking) vitamins and wellness products. This wellness subscription box ships personalized daily vitamin packs along with additional wellness items to your doorstep each month.

To get started, fill out the personalized quiz about your diet and lifestyle. Care/of will build you your own custom health plan, backed by actual science and vetted by nutritionists. All Care/of products are made from the most effective bio-available ingredients possible, designed to help you feel your very best. They’re also sustainably sourced.

Each box comes with 30 individual packs of vitamins. Your daily pack contains your curated mix of supplements — perfect to grab on the go. Keep forgetting to take your Care/of each day? Try using their app, where you can track how many days in a row you use your packs. You’ll achieve milestones with longer and longer streaks.

If you’ve got a good idea of your nutritional needs, you can build your own mix from their line of 30 vitamins, minerals, probiotics, powders, and more. Modify your custom vitamin packs at any time and try out new supplements whenever you’d like.

Our readers love the versatility of this wellness subscription box; it’s an excellent way to upgrade your vitamins without spending a ton of time on research.

Pros

Offers vitamins, minerals, herbs, probiotics, collagen, and protein.

Most individual ingredients are relatively affordable

Subscription plans are easy to modify based on your current needs.

Cons

Shipping fee for orders less than $20.

Mostly geared towards women's needs (but men can still use most products)

Very few options for vitamin/supplement blends

WHAT OUR READERS SAY:

“I love the variety and personalization.” – J

Shipping: Ships for free to the U.S. and Canada.

Starting at $20.00

If you want to learn more, check out all our Care/of - Personalized Daily Vitamins reviews.

3. Rootine

Best Blood Test/DNA-Based Vitamin Subscription Service

The Cost: Smart Multivitamin costs $94/month. At-home lab tests cost $125.

What This Vitamin Subscription Delivers:

Rootine is a multivitamin subscription service offering users a completely custom formula based on an online lifestyle quiz, and an at-home DNA and blood test (users can also upload results from existing 23andMe or Ancestry.com accounts). Rootine's slow-release microbead delivery system ensures maximum absorption and accurate dose measurement–no capsules involved.

Start by taking the lifestyle quiz, which provides recommended nutrients and detailed explanations. Users can choose to proceed with the personalized nutrients, or they can go ahead with the DNA testing and blood testing, which personalizes the nutrient profile even further. Uniquely, users can continuously re-test and optimize their multivitamins for peak wellness.

Subscribers will receive Rootine's Smart Multivitamin which includes up to 20 clinically-backed nutrients. You can take your vitamin packs as is with water or easily add the microbeads into meals.

Pros

DNA and blood test-based

Unique microbead delivery system provides maximum results

Way more optimized for your specific health needs than other brands

Cons

Much more expensive than other vitamin subscriptions

Can't customize vitamin packs easily

There is no month-to-month subscription option

Shipping: Rootine ships within the U.S. only, including Alaska and Hawaii. Rootine does not ship to Puerto Rico, Guam, or the US Virgin Islands.

Starting at $94.00

If you want to learn more, check out all our Rootine reviews.

4. Persona

Personalized Vitamin Service with Highest Number of Individual Products

The Cost: Individual ingredients range from $2.80-$39.48 (28 day supply). Save with bundles.

What This Vitamin Subscription Delivers:

Want to step up your vitamin and supplement game, but don't want to spend a fortune on buying 20+ individual products? Persona offers one of the most personalized vitamin subscription services available today.

Customers can create a fully customized vitamin subscription by completing an online assessment or they can choose from among several curated vitamin packs if they only want to use a few ingredients to focus on a single health area.

To create the perfect personalized vitamin packs for your specific health goals, you'll need to take Persona's online assessment. It's extremely thorough compared to most other vitamin quizzes and asks questions about medical history, medication use, health goals, and more. Once you've completed the assessment, Persona will apply its scientifically-backed algorithm in order to develop a personalized vitamin pack that's designed to meet your specific health needs.

Customers will receive both morning and evening vitamin packs that contain a different set of ingredients depending on their desired health outcomes.

Customers may also choose to select curated vitamin packs that are centered on more specific health goals, such as weight loss support, energy, or sleep. Since these vitamin packs typically contain half of the ingredients that come in Persona's personalized vitamin packs, they are usually cheaper, but the only catch is that you cannot add or remove ingredients from these packs.

While prices and ingredients vary, you can expect to pay around $60-100/month for a customized vitamin pack that contains around 6-10 ingredients whereas curated packs cost anywhere from $21.99 to $30.99 for 3-ingredient packs and up to $73.99 to $83.9 for 5-ingredient packs.

Pros

Asks in-depth questions in their quiz including medical history and medication use.

Considers supplement-drug interactions.

Offers curated vitamin packs for specific concerns that tend to be cheaper than the personalized packs.

Cons

Options can be overwhelming for people new to supplements.

Some packs come with a ton of pills.

Shipping: Ships to the U.S. and worldwide. Free shipping is available on occasion to the U.S. Shipping rates are $5-$25 per shipment for international countries.

Starting at $21.00

If you want to learn more, check out all our Persona reviews.

5. mindbodygreen

Best Vitamin and Supplement Subscription for Targeting Whole Health

The Cost: Individual products range in price and you can expect to pay around $50+ per bottle per month.

What This Vitamin Subscription Delivers:

mindbodygreen is a lifestyle media brand dedicated to inspiring you to live your best life – mentally, physically, spiritually, and emotionally. Through a 360º approach to wellness that weaves the mental, physical, spiritual, emotional, and environmental aspects of well-being together, mindbodygreen has been a respected resource for over ten years for individuals looking deeper into the fundamentals of science-based holistic well-being.

mindbodygreen has expanded over the years into functional nutrition coaching, classes (varying from fitness to self-improvement), and then most recently, supplements. Their current supplements range from probiotics+, sleep support+, immune support, and cellular beauty (just to name a few).

We particularly love mindbodygreen's Ultimate Multivitamin+, a daily vitamin that includes 33 premium ingredients: 14 vitamins, 13 minerals, and six botanical bioactives.

mindbodygreen's site explains this multivitamin as:

a high-potency vegan formula delivers a complete array of essential vitamins, chelated and marine minerals, a built-in B complex leveraging methylation technology, algal vitamin D3, and longevity botanicals including glutathione, resveratrol, piperine, and a bouquet of carotenoids. In this next-generation multi for women and men, we optimized the dose, bioavailability, bioactivity, and gentleness of each ingredient.

The site is full of supplement options that are organized in a large drop-down menu that's easy to navigate. Once you choose a supplement, its page has an informative timeline at the bottom that illustrates how many weeks it will take to feel the effects of each ingredient in the supplement. There are also descriptions of each ingredient underneath the timeline, to help you better understand why they're included and how they benefit your body.

Pros

Contains 33 nutrients

Only need to take 2 capsules per day

Vegan-friendly and free of dairy, gluten, and soy

Cons

On the pricier side at $59 per month.

Is not personalized to your unique needs.

Some people may prefer to keep botanicals and other supps separate from vitamins.

Shipping: Ships free to the United States, including Hawaii, Alaska, all US territories, and Canada.

Starting at $69.00

Active Deal

Save 15% off your first month! New subscriptions only; code cannot be combined with other offers.

Use Coupon Code MSA15

If you want to learn more, check out all our mindbodygreen probiotic+ reviews.

6. GEM

Best Vitamin and Supplement Subscription for Whole Food Based Vitamins

The Cost: Starting at $55 per month.

What This Vitamin Subscription Delivers:

Forget what you know about traditional pills and powders – GEM believes in eating your vitamins in the way nature intended. Their real-food multivitamin Bites are designed to work with your daily nutrition and absorb properly into your body. Plus, it’s a lot more fun to eat than it is to take.

Backed by a multidisciplinary Scientific Advisory Board and the ancient wisdom of synergistic whole foods, GEM is a daily bite to remind you to trust (and nourish) your gut.

Pros

Vegan, soy and gluten free

Made from whole foods

Chewable

Cons

On the pricier side at $55 per month.

Is not personalized to your unique needs.

Not a complete multivitamin

Shipping: Free shipping on orders over $60.

Starting at $55.00

Active Deal

Save 30% on the real food multivitamin you EAT, not take

Use Coupon Code MSA30

If you want to learn more, check out all our GEM reviews.

Have you tried any of these vitamin subscription services? If so, what did you think? Make sure to leave a comment below and share your experience if you've used any of these brands that offer personalized vitamins and dietary supplements.

Check Out Other Top Subscriptions

See more readers' and editors' picks on articles below.

Posted in Best Subscription Boxes, Healthy Subscription Boxes, Vitamins & Supplements

Kathryn Brooke

Hey, I'm Kat! I’m a mom of two who loves sharing about brands that help me juggle work, family life, and my passions.

Most days, I'm balancing my role as Marketing Content & SEO Manager at SUCCESS® with homeschooling my littles. In my free time, you can find me at the gym, hanging out at a local park, or splurging on specialty coffee.

Want to connect? Add me on LinkedIn!

Go-To Brands:

👗Personal styling: Wantable

🍷Wine and cheese: MonthlyClubs

☕️Specialty coffee: Trade Coffee

Read More By Kathryn Brooke >

Kathryn Brooke

Read More By Kathryn Brooke >

Hey, I'm Kat! I’m a mom of two who loves sharing about brands that help me juggle work, family life, and my passions.

Most days, I'm balancing my role as Marketing Content & SEO Manager at SUCCESS® with homeschooling my littles. In my free time, you can find me at the gym, hanging out at a local park, or splurging on specialty coffee.

Want to connect? Add me on LinkedIn!

Go-To Brands:

👗Personal styling: Wantable

🍷Wine and cheese: MonthlyClubs

☕️Specialty coffee: Trade Coffee

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Our reviewers research, test, and recommend the best subscriptions and products independently; click to learn more about our editorial guidelines. We may receive commissions on purchases made through links on our site.